Open Your Mind

Exercise and Osteoarthritis Rethinking a Familiar Recommendation For years, people diagnosed with osteoarthritis have heard the same advice almost immediately after leaving the clinic. Move more. Strengthen the muscles. Stay active. The message is repeated so often that it begins to sound less like medical guidance and more like a universal rule. And to be fair, the logic behind it makes sense. If joints become stiff and painful, improving mobility and muscle support should help stabilize movement. Many patients genuinely feel some relief when they begin gentle routines such as walking, light resistance training, or guided physiotherapy. However, a large new analysis suggests the situation may be more complicated than the familiar recommendation implies. Researchers reviewing decades of clinical evidence found that the real impact of exercise on osteoarthritis pain and function may be smaller and shorter lived than many people expect. The findings, published through BMJ Group in the jo...

  Rethinking Cancer Treatment When Less Medicine Starts Doing More For decades, the logic behind cancer treatment has leaned in one direction. Stronger drugs, higher doses, more aggressive protocols. The assumption felt intuitive. If a disease is dangerous, the response should be even stronger. Many oncologists were trained within that framework, and for good reason, because earlier generations of therapies often required that kind of intensity to make any measurable difference. Yet medicine has a way of humbling its own assumptions. Every few years, a study appears that quietly suggests the body does not always respond the way we expect. Instead of more treatment producing better outcomes, sometimes the opposite happens. That idea might sound counterintuitive at first, but modern immunotherapy is beginning to reveal exactly that pattern. A recent investigation from Karolinska Institutet explored something surprisingly simple. What happens if one of the key drugs used in advanced m...